Clinical Study
Clinical Activity and Tolerability of a 14-Day Infusional Ifosfamide Schedule in Soft-Tissue Sarcoma
Table 1
Patient characteristics.
| Total | 35 | Age (median, range) | 53 (27–76) |
| | (%) |
| Sex | | Male | 16 (45.7%) | Female | 19 (54.3%) | ECOG performance status at baseline | | 0 | 1 (2.8%) | 1 | 30 (85.7%) | 2 | 4 (11.4%) | Histology | | De-differentiated liposarcoma | 22 (62.8%) | Synovial sarcoma | 7 (20%) | Myxoid/round-cell liposarcoma | 3 (8.5%) | Other | 3 (8.5%) | Previous chemotherapy | | Chemotherapy naive | 23 (65.7%) | Ifosfamide-containing regimen | 9 (25.7%) | Nonifosfamide-containing regimen | 3 (8.5%) | Previous surgery | | Yes | 23 (65.7%) | No | 12 (34.3%) | Baseline creatinine clearance (Cockroft-Gault formula) | | Median | 97 mL/min (51.9–215.8) | Baseline albumin | | Median | 35 g/L (21–43) |
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