Research Article
Adult versus Pediatric Neuroblastoma: The M.D. Anderson Cancer Center Experience
Table 1
Patient characteristics by stage of disease.
| | | Adult (%) | Pediatric (%) |
| | Stage: L1 | 57 (48) | 24 (22%) | | Median age (range) | 48 (18–77) | 5.5 (3–15) | | Histology | | | | Ganglioneuroblastoma | 6 (11) | 6 (25) | | Neuroblastoma | 51 (89) | 18 (75) | | Primary location | | | | Bones, skeletal system | 1 (2) | 1 (4) | | Central nervous system | 1 (2) | 1 (4) | | Chest cavity viscera | 2 (4) | 4 (17) | | Head and neck | 46 (81) | 3 (12) | | Soft tissue | 2 (4) | 8 (33) | | Urinary tract | 5 (9) | 7 (29) | | Stage: L2 | 44 (37) | 12 (11) | | Median age (range) | 51.5 (20–81) | 5.5 (3–10) | | Histology | | | | Ganglioneuroblastoma | 2 (5) | 3 (25) | | Neuroblastoma | 42 (95) | 9 (75) | | Primary location | | | | Central nervous system | 3 (7) | 2 (17) | | Chest cavity viscera | 2 (5) | 1 (8) | | Head and neck | 32 (73) | 1 (8) | | Soft tissue | 3 (7) | 5 (42) | | Urinary tract | 4 (9) | 3 (25) | | Stage: M | 17 (14) | 74 (67) | | Median age (range) | 29 (19–75) | 5 (3–16) | | Histology | | | | Ganglioneuroblastoma | 1 (16) | 4 (5) | | Neuroblastoma | 16 (94) | 70 (95) | | Primary location | | | | Abdominal cavity viscera | 2 (12) | 1 (1) | | Central nervous system | 0 | 1 (1) | | Chest cavity viscera | 1 (6) | 5 (7) | | Male genital system | 1 (6) | 0 | | Head and neck | 4 (24) | 2 (3) | | Metastatic cancer | 1 (6) | 1 (1) | | Soft tissue | 4 (24) | 25 (34) | | Genitourinary tract* | 4 (24) | 39 (53) |
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Includes adrenal primary.
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