Table 6: Comparison of published reports detailing characteristics of patients with brain metastases from malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma.

Case authorAge, sex IB yr.BM treatmentOS Mo

Malignant peripheral nerve sheath tumors
Xu et al., 2012 [93]8 M14(None)16
Flannery et al., 2010 [15]34 F36SR, WBRT, GKSRS48
Tilgner et al., 2007 [92]60 M0aSR, WBRTAlive at 14
Park et al., 2007 [101]21 M0aSR, WBRT, Chemo16
van Eck and Horstmann, 2006 [100]83 M108SR, GKSRS122
Matyja et al., 2004 [94]33 M~56SR~60
Yone et al., 2004 [104]4 M7WBRT21
Oishi et al., 2000 [102]48 M61SR (en bloc)NR
Maschke et al., 1999 [105]17 F0aSRNR
Probst-Cousin et al., 1997 [106]19 F156None157
Haisa et al., 1996 [103]58 F180SR (en bloc)181
Fenzi et al., 1995 [99]45 F5None18
Seppälä and Haltia, 1993 [107]13 M2None2
D'Angelo et al., 1991 [115]68 F24SR (en bloc)36
Valdueza et al., 1991 [108]47 M~13None18
Cras et al., 1990 [109]46 F0None0
Hirose et al., 1989 [110]53 M15SR (en bloc), chemoAlive at 20b
Hasegawa et al., 1984 [111]51 M2Biopsies3
Macaulay, 1978 [112]18 M2None2
White Jr., 1971 [113]20 MNRSR, radiation7
D’Agostino et al., 1963 [114]22 FNRNR68

Angiosarcoma
Liassides et al., 2004 [119]24 F3Palliative6
Eguchi et al., 2002 [123]64 M19Palliative0
Chami et al., 1994 [118]59 MNRPalliativeNR
Vaquero et al., 1990 [124]30 M4SR6
Kuratsu et al., 1991 [117]17 MSR12
Haft et al., 1988 [80]31 FWBRTNR
Akutsu et al., 2004 [125]53 M2SR6
Ellegala et al., 2002 [121]76 M24SR2
Søndenaa et al., 1993 [126]73 F3Palliative3
Gallo et al., 2001 [127]33 M12SR0
Hassane et al., 2010 [128]48 M3Palliative0
Simpson et al., 1989 [32]21 M24SR, WBRT 26b
Angrish et al., 1979 [120] 38 M3Palliative0
Plotnik et al., 2008 [122]61 F60SRNR
Chaudhuri et al., 1980 [129]31 F72SR, WBRT2
Macaulay, 1978 [112]18 M2Palliative0

IB: interval to brain metastasis (mo); OS: overall survival in months; M: male; F: female; chemo: chemotherapy; SR: surgical resection; GKSRS: Gamma knife stereotactic radiosurgery; ICH: intracerebral hemorrhage on presentation; WBRT: whole brain radiotherapy; RT: radiotherapy; D: death prior to treatment; NR: not reported; NF: associated with neurofibromatosis type-1; abrain metastasis at initial presentation.; balive at last follow-up without recurrence.