Brain Metastasis in Bone and Soft Tissue Cancers: A Review of Incidence, Interventions, and Outcomes

Table 6

Comparison of published reports detailing characteristics of patients with brain metastases from malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma.

Case author	Age, sex	IB yr.	BM treatment	OS Mo
Malignant peripheral nerve sheath tumors
Xu et al., 2012 [93]	8 M	14	(None)	16
Flannery et al., 2010 [15]	34 F	36	SR, WBRT, GKSRS	48
Tilgner et al., 2007 [92]	60 M	0^a	SR, WBRT	Alive at 14
Park et al., 2007 [101]	21 M	0^a	SR, WBRT, Chemo	16
van Eck and Horstmann, 2006 [100]	83 M	108	SR, GKSRS	122
Matyja et al., 2004 [94]	33 M	~56	SR	~60
Yone et al., 2004 [104]	4 M	7	WBRT	21
Oishi et al., 2000 [102]	48 M	61	SR (en bloc)	NR
Maschke et al., 1999 [105]	17 F	0^a	SR	NR
Probst-Cousin et al., 1997 [106]	19 F	156	None	157
Haisa et al., 1996 [103]	58 F	180	SR (en bloc)	181
Fenzi et al., 1995 [99]	45 F	5	None	18
Seppälä and Haltia, 1993 [107]	13 M	2	None	2
D'Angelo et al., 1991 [115]	68 F	24	SR (en bloc)	36
Valdueza et al., 1991 [108]	47 M	~13	None	18
Cras et al., 1990 [109]	46 F	0	None	0
Hirose et al., 1989 [110]	53 M	15	SR (en bloc), chemo	Alive at 20^b
Hasegawa et al., 1984 [111]	51 M	2	Biopsies	3
Macaulay, 1978 [112]	18 M	2	None	2
White Jr., 1971 [113]	20 M	NR	SR, radiation	7
D’Agostino et al., 1963 [114]	22 F	NR	NR	68
Angiosarcoma
Liassides et al., 2004 [119]	24 F	3	Palliative	6
Eguchi et al., 2002 [123]	64 M	19	Palliative	0
Chami et al., 1994 [118]	59 M	NR	Palliative	NR
Vaquero et al., 1990 [124]	30 M	4	SR	6
Kuratsu et al., 1991 [117]	17 M	—	SR	12
Haft et al., 1988 [80]	31 F	—	WBRT	NR
Akutsu et al., 2004 [125]	53 M	2	SR	6
Ellegala et al., 2002 [121]	76 M	24	SR	2
Søndenaa et al., 1993 [126]	73 F	3	Palliative	3
Gallo et al., 2001 [127]	33 M	12	SR	0
Hassane et al., 2010 [128]	48 M	3	Palliative	0
Simpson et al., 1989 [32]	21 M	24	SR, WBRT	26^b
Angrish et al., 1979 [120]	38 M	3	Palliative	0
Plotnik et al., 2008 [122]	61 F	60	SR	NR
Chaudhuri et al., 1980 [129]	31 F	72	SR, WBRT	2
Macaulay, 1978 [112]	18 M	2	Palliative	0

IB: interval to brain metastasis (mo); OS: overall survival in months; M: male; F: female; chemo: chemotherapy; SR: surgical resection; GKSRS: Gamma knife stereotactic radiosurgery; ICH: intracerebral hemorrhage on presentation; WBRT: whole brain radiotherapy; RT: radiotherapy; D: death prior to treatment; NR: not reported; NF: associated with neurofibromatosis type-1; ^abrain metastasis at initial presentation.; ^balive at last follow-up without recurrence.