Table 7: Calculation of costs of posttreatment anticancer therapy.

TreatmentMedication costaAdministration costsb
Mg per tab or vialCost per tab or vial, £Cost per mg, £Cost per administration, £Expected days of use per courseCost per course of therapy, £Cost per administration, £Expected days of use per courseCost per course of therapy, £Total cost per course
of therapy, £

Cyclophosphamide50060306.141873306.142,0272,214
Dacarbazine1,000320683.352292053.35686915
Doxorubicin20027511812.855152052.855831,098
Etoposide1001201330.6840020530.686,2806,681
Etoposide + ifosfamide (+mesna)
 Etoposide1001201326.3034320526.305,383
 Ifosfamide1,00044021715.783,43030215.781,539
 Mesna400404615.7872515.78
 Total4,4996,92211,421
Gemcitabine1,5002140.1419713.572,67420513.572,7785,451
Gemcitabine + docetaxel (+lenograstim)
 Gemcitabine 1,5002140.141858.901,6432058.901,821
 Docetaxel1407205.146764.453,0074.45
 Lenograstim0.26362.542386431.141,9880.5731.1418
 Total6,6391,8398,478
Ifosfamide (+mesna)
 Ifosfamide1,00044021715.783,43030215.784,769
 Mesna400404615.7872515.78
 Total4,1564,7698,924
Sorafenib20027071114.378,096124.08498,145
Sunitinib12.52829965.336,489121.56196,508
Temozolomide2501360.5430410923.672,570120.85102,580
Trabectedin11,3661,3663,1673.4010,7683303.401,12311,891

Tab: tablet; unit costs of medications based on British National Formulary [32, 35]; bfacility costs for administration of intravenous therapies are based on a weighted average of the outpatient, day case, and other 2010/2011 NHS Reference Costs for delivery of a chemotherapy cycle (SB12Z deliver simple parenteral chemotherapy at first attendance, and SB14Z deliver complex chemotherapy, including prolonged infusional treatment at first attendance for infusion of more than 24 hours) [35]. Assume dispensing costs of oral medications are based on the cost of a community pharmacist (15 minutes) [34].