Table 3: Case-specific data of SSI patients of malignant musculoskeletal tumors.

Age/sexDiagnosisSiteSurgical procedureReconstructionDuration of surgery (min)Blood loss (g)Isolated bacteria from SSITreatment for SSIOncological outcome/SSI healingTreatment duration for SSI (month)

162/FMetastatic bone tumorSacrumMarginal resectionArtificial mesh355978MRSAAntibiotics, HBOT, surgeryDOD/not healed18
261/MChondrosarcomaFemurWide resectionPasteurized autograft, plate and screw383500CNSAntibiotics, HBOT, surgeryCDF/healed12
362/MMetastatic bone tumor (thyroid)HumerusMarginal resectionTumor-prosthesis 397270MSSAAntibiotics, HBOT, surgeryDOD/healed5
413/MOsteosarcomaTibiaWide resectionTumor-prosthesis
Gastrocnemius muscle flap
445470MRSAAntibiotics, HBOT, surgeryCDF/healed9
535/MOsteosarcomaPelvisHemipelvectomyLiquid-nitrogen treated autograft, plate and screw, external fixator8904090CNSAntibiotics, HBOT, surgeryDOD/not healed12
661/MMetastatic bone tumor (kidney)FemurWide resectionTumor-prosthesis, Sartorius muscle flap514600MSSAAntibiotics, surgery (amputation) AWD/healed1
745/MMyxoid liposarcomaThighWide resection including FemurPasteurized autograft, plate and screw6801620MRSAAntibiotics, HBOT, surgeryDOD/not healed18
879/FMFHButtockWide resectionGluteal artery perforator flap14550MRSAAntibiotics, HBOTDOO/not healed9
964/MMFHThighMarginal resectionNone5082505Pseudomonas aeruginosa Antibiotics, HBOT, surgeryDOD/not healed9
1082/MDedifferentiated liposarcomaThighDisarticulation of hipNone391220Enterobacter cloacae Antibiotics, surgeryCDF/healed5
1145/MMyxoid liposarcomaThighWide resection including FemurPasteurized autograft, plate and screw550470CNSAntibiotics, HBOT, surgeryCDF/healed18
1275/MMFHLower legWide resection including TibiaBone cement, intramedullary nail, Gastrocnemius muscle flap, FTSG283255CNSAntibiotics, HBOT, surgery (local flap) CDF/not healed21
1330/MMFHGroinWide resectionNone250105Pseudomonas aeruginosa Antibiotics, HBOT, surgery (rectus abdominis muscle flap) CDF/not healed3
1470/FMFHThighMarginal resectionGastrocnemius muscle flap, FTSG16330MSSAAntibiotics, HBOT, NPWTCDF/healed3
1559/MMFHThighWide resectionNone1460MSSAAntibiotics, HBOT, AWD/healed1
1673/FChondrosarcomaHandMarginal resection including metatarsal boneIliac autograft, Kirschner wire524685Enterobacter cloacae Antibiotics, surgery (forearm flap) CDF/healed20
1773/FMFHThighWide resectionFree latissimus dorsi flap, STSG626190MRSAAntibiotics, HBOT, surgery, NPWTAWD/healed3
1868/FUndifferentiated sarcomaThighWide resectionSTSG18930MRSAAntibioticsCDF/healed2

MFH: malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma); FTSG: full-thickness skin graft; STSG: split-thickness skin graft; MSSA: methicillin-sensitive Staphylococcus aureus; mRSA: Methicillin-resistant Staphylococcus aureus; CNS: coagulase-negative staphylococci; HBOT: hyperbaric oxygen therapy; NPWT: negative-pressure wound therapy; CDF: continuous disease free; DOD: died of disease; DOO: died of other cause (Case 8, uterine cervical cancer); AWD: alive with disease.