Table 3: Patient characteristics by Charlson Comorbidity Index score .

(%)Charlson Comorbidity Index score (%) -value
0123+

Number453 (100)368 (81)37 (8)27 (6)21 (5)
Age (years)
 Median (range)46 (15–90)40 (15–90)62 (17–83)59 (17–81)64 (21–86)<0.001
Sex
 Female179 (40)137 (37)20 (54)12 (44)10 (48)
 Male274 (60)231 (63)17 (46)15 (56)11 (52)0.18
Year of diagnosis
 1979–1988131 (29)116 (32)10 (27)0 (0)5 (24)
 1989–1998129 (28)103 (28)8 (22)12 (44)6 (29)
 1999–2008193 (43)149 (40)19 (51)15 (56)10 (48)0.027
Stage at diagnosis
 Localized387 (85)321 (87)32 (86)18 (67)16 (76)
 Metastatic66 (15)47 (13)5 (14)9 (33)5 (24)0.018
Tumor size (cm)
 Median (range) 8 (1–30)8 (1–30)8 (2–30)7 (2–15)10 (3–23)0.14
Soft tissue involvement
 No86 (19)71 (19)5 (14)4 (15)6 (29)
 Yes367 (81)297 (81)32 (86)23 (85)15 (71)0.51
Malignancy grade
 1107 (24)86 (23)11 (30)7 (26)3 (14)
 269 (15)55 (15)8 (22)4 (15)2 (10)
 3277 (61)227 (62)18 (50)16 (59)16 (76)0.59
Histological type
 Ewing/osteosarcoma176 (39)149 (40)10 (27)9 (33)8 (38)
 Others277 (61)219 (60)27 (73)18 (67)13 (62)0.40
Treatment
 Surgery389 (86)325 (88)30 (81)19 (70)15 (71)0.009
 Type
  Resection257 (66)213 (66)19 (63)13 (76)12 (80)
  Amputation130 (34)112 (34)11 (37)4 (24)3 (20)<0.001
 Margin
  Wide/radical269 (70)228 (70)19 (63)13 (76)9 (60)
  Intralesional/marginal117 (30)96 (30)11 (37)4 (24)6 (40)<0.001
 Radiotherapy83 (18)71 (19)5 (14)3 (11)4 (19)0.63
 Chemotherapy135 (30)119 (32)4 (11)8 (30)4 (19)0.005
  Curative106 (79)98 (82)2 (50)3 (38)3 (75)
  Palliative29 (21)21 (18)2 (50)5 (63)1 (25)0.012

Note: tumor size: 38 missing. Type of surgery: 2 missing. Surgical margin: 3 missing.