Analysis of the Intratumoral Adaptive Immune Response in Well Differentiated and Dedifferentiated Retroperitoneal Liposarcoma

Figure 3

Intratumoral tertiary lymphoid structures (TLS) in WD/DD retroperitoneal liposarcoma. (a) General histologic appearance of TLS with varying levels of complexity and size, 100x magnification. (b) Immunohistochemistry for DC-LAMP (brown dots), a marker for mature dendritic cells, CD4 (red) and CD8 (green). Green boxes denote areas with DC-LAMP positive cells. 400x magnification. (c) Clinical outcome for patients with and without intratumoral TLS with recurrence-free survival (RFS) and overall survival (OS) shown.

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