A Quantitative Structure-Activity Relationship and Molecular Modeling Study on a Series of Biaryl Imidazole Derivatives Acting as H⁺/K⁺-ATPase Inhibitors

Figure 4

The model showing hydrophobic interactions of predicted compound 5 (Table 2) with the enzyme H⁺/K⁺-ATPase. The red surface shows strong hydrophobic zone and the blue one low hydrophobic zone.