Schizophrenia Research and Treatment

Research Article

Ultrastructural Alterations of Myelinated Fibers and Oligodendrocytes in the Prefrontal Cortex in Schizophrenia: A Postmortem Morphometric Study

Table 1

Basic demographic characteristics (Means, SD).
SubjectsNumber per groupGenderAge (years)PMI (hours)Duration of illness (years)Age at onset of illness (years)
Gray matter
Controls 𝑁 = 4 0 29 M, 11 F55,5 ± 14,25,9 ± 1,2  
Schizophrenia 𝑁 = 4 0 15 M, 25 F58,7 ± 15,66,3 ± 1,825,1 ± 12,833,1 ± 14,8
SPNS 𝑁 = 2 0 6 M, 14 F59,7 ± 16,55,7 ± 1,427,4 ± 12,532,2 ± 14,8
SPPS 𝑁 = 1 8 8 M, 10 F56,6 ± 15,26,7 ± 2,121,9 ± 14,534,7 ± 15,4
White matter
Controls 𝑁 = 1 2 8 M, 4 F51,1 ± 14,06,5 ± 1,2  
Schizophrenia 𝑁 = 1 2 7 M, 5 F51,1 ± 19,06,5 ± 1,227,0 ± 12,824,1 ± 12,6
SPNS 𝑁 = 6 4 M, 2 F55,5 ± 21,06,1 ± 1,030,0 ± 14,025,5 ± 13,5
SPPS 𝑁 = 6 3 M, 3 F46,7 ± 17,67,0 ± 1,324,0 ± 12,022,7 ± 12,7
SPNS: schizophrenia with predominantly negative symptoms.
SPPS: schizophrenia with predominantly positive symptoms.