Review Article

Parietal Lobes in Schizophrenia: Do They Matter?

Table 1

Studies reporting lesions in parietal lobe.

InvestigatorLesion siteSubjectsAffected function/impairmentConclusionType of study

Danckert et al.
2002 [14]
Right PL1 patient with visual neglectImagined movements did not show the same speed-accuracy trade-off observed for actual movementsRight parietal lobe may be important in the generation of internal models of motor movementsCase report

Doricchi and Tomaiuolo 2004 [15]Right hemispheric damage21 pts with neglect
10 ctrls
NeglectMaximal overlap in supramarginal gyrus and superior longitudinal fasciculus; decisive role of parieto-frontal disconnection in neglectCase series

Haaland et al.
2000 [16]
Left PL41 pts with damage in left hemisphereIdeomotor apraxiaRegions in the left hemisphere important for goal directed movementsCase series

Markowitsch et al. 1999 [17]Left angular gyrus lesion1 patientAuditory working memory dysfunctionCalculation tasks were not affectedCase report

Paterson and Zangwill 1944 [18]Penetrating head wound affecting the angular gyrus1 patientNeglectCase report

Rosler et al. 1997 [19]Ischemic lesion in the territory of the right middle cerebral artery31 pts with right- or left- sided infarctions
31 ctrls
Facial recognition ability in pts with right-sided lesions was lessened compared with ctrls and with pts with left-sided infarctionsGraded impairment in patients with right middle cerebral artery infarctsCross-sectional case-control study

Rossetti et al.
2005 [20]
First case: bilateral parietal damage
Second case: bilateral posterior parietal and upper and lateral occipital cortico-subcortical regions bilaterally through ischemic stroke
2 ptsFirst case: visual disorientation, simultanagnosia, and severe optic ataxia
Second case: bilateral optic ataxia
Optic ataxia patients are impaired for immediate visuomotor processing but improve when required to delay before responding.Case series

Sirigu et al. 1999 [21]Left parietal cortex damage3 pts with apraxia
6 ctrls with apraxia
2 nonapraxic neurological ctrs
pts were impaired in recognition of the viewed hand as the examiner's when it performed movements similar to their own movementParietal cortex is important for the perception of own movements as self-generatedCross-sectional

PL: parietal lobe; pts: patients; ctrls: healthy controls.