Research Article

Very Low-Dose Risperidone in First-Episode Psychosis: A Safe and Effective Way to Initiate Treatment

Table 1

Sociodemographic and illness-related characteristics of the participants ( 𝑁 = 9 6 ).

Fast responders * 𝑁 = 3 7 Slow responders * 𝑁 = 2 6 Withdrawn 𝑁 = 3 3 𝑃 value

Sex (% male)75.7%69.2%75.8%.81

Mean age at admission, years (SD)21.1 (3.7)21.6 (4.0)21.8 (3.4).75

Age at onset of psychotic symptoms, years (SD)20.5 (3.5)21.0 (3.8)21.1 (3.5).77

Marital status (% never married)81.1%80.8%90.9%.44

Education (% post-secondary)13.5%19.2%18.8%.79

Diagnosis:
 Schizophrenia/schizophreniform33 (89.2%)19 (73.1%)22 (66.7%)
 Schizoaffective/delusional/NOS4 (10.8%)4 (15.4%)5 (15.2%)
 Affective disorder0 (0%)3 (11.5%)6 (18.2%).094

Duration of untreated psychosis mean, (SD) and median ( 𝑀 ) days225.2 (269.8) 𝑀 = 1 1 2 . 0 267.1 (416.5) 𝑀 = 9 5 . 0 247.5 (370.5) 𝑀 = 1 5 1 . 0 .97

*Responder status determined after 4 weeks of risperidone at a dose of 2 mg/day.