Research Article
Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine: A Voxel-Based Morphometric Study
Table 2
Correlations between grey matter volumes after olanzapine treatment and body weight changes observed in schizophrenia patients.
| |
R/L | Regions based on AAL atlas | MNI Coordinates |
Voxels | Z-Score | P value | X | Y | Z |
| Positive correlations Body Weight Change and Brain Structures | R | Superior parietal | 37 | −50 | 59 | 1302 |
2.85 | .002 | R | Inferior frontal operculum | 50 | 8 | 18 | 1852 |
2.40 | .008 |
| Negative correlations Body Weight Change and Brain Structures | L | Post-central | −52 | −11 | 24 | 7107 |
3.32 | .0001 | L | Hippocampus | −33 | −20 | −13 | 1387 |
1.99 | .023 | R | Post-central | 45 | −15 | 34 | 3501 |
2.38 | .009 | L | Precuneus | −14 | −39 | 69 | 559 |
2.11 | .018 | L | Thalamus | −7 | −23 | 15 | 179 |
1.96 | .025 | R | Precuneus | 10 | −59 | 43 | 19 |
1.68 | .048 |
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