Research Article

The Impact of Childhood Adversity on the Clinical Features of Schizophrenia

Table 1

Clinical description of the sample by gender.

VariableMale patients ()Female patients ()Total

Age at onset, years24.9 ± 7.426.6 ± 7.925.8 ± 7.6
Duration of illness, years 10.8 ± 8.6 8.3 ± 7.2 9.6 ± 7.9
Duration of untreated illness, years 1.4 ± 1.8 1.5 ± 1.5 1.5 ± 1.7
Diagnostic subtype
 Paranoid222244
 Undifferentiated7512
 Catatonic224
 Disorganized22
Body mass index, kg/m2 23.2 ± 4.2 25.9 ± 5.4 24.5 ± 4.9
Blood pressure, mmHg
 Systolic118.3 ± 10.3115.1 ± 12.4116.7 ± 11.4
 Diastolic80.9 ± 10.277.5 ± 10.279.2 ± 10.2
Lifetime substance use disorder
 Total10313
 Nicotine dependence10313
 Alcohol abuse/dependence202
Lifetime suicide attempt 9 8 17
Lifetime violent suicide attempt549
CTQ scores
 Emotional abuse7.9 ± 3.98.0 ± 3.38.0 ± 3.6
 Physical abuse6.4 ± 2.95.7 ± 1.96.1 ± 2.4
 Sexual abuse5.0 ± 0.25.1 ± 0.45.0 ± 0.3
 Emotional neglect11.6 ± 3.511.5 ± 3.311.5 ± 3.4
 Physical neglect9.3 ± 2.79.6 ± 3.39.5 ± 3.0
 Total40.4 ± 10.439.9 ± 10.140.1 ± 10.2
PANSS scores
 Positive8.9 ± 2.28.9 ± 2.18.9 ± 2.2
 Negative15.4 ± 6.415.5 ± 6.315.5 ± 6.3
 General psychopathology24.5 ± 6.626.6 ± 7.525.6 ± 7.1
 Total48.8 ± 13.751.0 ± 14.449.9 ± 14.0
CDSS score, total 1.3 ± 2.3 1.5 ± 2.7 1.4 ± 2.5
FAST score
 Autonomy2.9 ± 2.63.8 ± 2.83.4 ± 2.7
 Occupational activity7.2 ± 4.87.7 ± 4.67.4 ± 4.7
 Cognitive functioning4.6 ± 3.05.2 ± 3.04.9 ± 3.0
 Finances1.8 ± 1.61.9 ± 1.81.9 ± 1.7
 Interpersonal relationships7.0 ± 4.98.6 ± 5.57.8 ± 5.2
 Leisure1.9 ± 1.62.5 ± 1.72.2 ± 1.6
 Total25.4 ± 16.729.6 ± 17.427.5 ± 17.0
GAF score 61.7 ± 11.5 58.9 ± 11.6 60.2 ± 11.5

PANSS: Positive and Negative Symptom Scale for Schizophrenia; CDSS: Calgary Depression Scale for Schizophrenia; CTQ: Childhood Trauma Questionnaire; FAST: Functional Assessment Short Test; GAF: Global Assessment of Functioning.
Difference is significant at .