Review Article

Change in Prolactin Levels in Pediatric Patients Given Antipsychotics for Schizophrenia and Schizophrenia Spectrum Disorders: A Network Meta-Analysis

Table 1

Summary of the characteristics of the included trials.

StudyDiagnosisCriteria used for diagnosisTreatment duration
(weeks)
Follow-up assessment of prolactin levels (weeks)Inclusion criteria

Findling et al. 2012 [19]SchizophreniaDSM-IV-TR + K-SADS-PL66Inpatients or outpatients aged 13–17 years; PANSS ≥ 60
Findling et al. 2008 [20]SchizophreniaDSM-IV66Aged 13–17 years; PANSS ≥ 70
Haas et al. 2009 [21]SchizophreniaDSM-IV + K-SADS-PL66Aged 13–17 years; PANSS 60–120
Kryzhanovskaya et al. 2009 [22]SchizophreniaDSM-IV-TR66Aged 13–17 years; BPRS ≥ 35
Singh et al. 2011 [23]SchizophreniaDSM-IV + K-SADS-PL66Aged 12–17 years; weight ≥ 29 kg; PANSS 60–120

DSM: Diagnostic and Statistical Manual; TR: text revision; K-SADS-PL: Kiddie-Sads-Present and Lifetime; PANSS: Positive and Negative Syndrome Scale [14].