Research Article

Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss

Figure 3

hMNPs cause neurite branching in vitro. Neurite length was significantly longer ( 𝑃 < . 0 5 ) in cortical neuron cultures exposed to hMNP-conditioned media (a) for 7 days as compared to cortical neuron cultures exposed to control MN differentiation media (b). (c) The length of neurites in cultures exposed to hMNPconditioned media as compared to those exposed to control media was significantly higher ( 𝑃 < . 0 5 ). Bar = 50 μm.
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207230.fig.003b
(b)
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(c)