Review Article
Advances in Cell Transplantation Therapy for Diseased Myocardium
Table 1
Cell transplantation by intramyocardial injection and vascular infusion in clinical studies.
| Cell injection to myocardium | Cell type | ×106 cells | Function | Remarks | |
| Myoblast | … | ↑ | Arrhythmogenic potential | [20] | Myoblast | 206 | No effect | Arrhythmogenic potential | [21] | Myoblast | 400–800 | No effect | Arrhythmia | [14] | Myoblast | 870 | … | Arrhythmogenic potential | [22] | Myoblast, BMSC | 300, 100 | ↑ | | [15] |
| Vascular infusion | Cell type | ×106 cells | Function | Remarks | |
| BMSC | ~1.5–9 | … | Restoration of coronary flow reserve | [12] | BMSC | 39 | ↑ | | [13] | BMSC | 68 | No effect | | [11] | BMSC | ~100–300 | ↑ | Lower mortality | [8] | BMSC | 200–400 | No effect | Infarct remodelling | [10] | BMSC | 56–60 000 | ↑ | | [9] |
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BMSC: bone marrow stem cell.
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