Expression Patterns of Cancer-Testis Antigens in Human Embryonic Stem Cells and Their Cell Derivatives Indicate Lineage Tracks

<table>Gene expression profiles of CTAs in mouse ES, EG, and EC cells and in mouse germ line cells. (a) Pluripotent ES and EG cells and nullipotent EC cells express alkaline phosphatase and Oct4 and develop EBs; ES and EG cells differentiate into derivatives of three germ layers in teratomas (TES, TEG) while EC cells grow in vivo as malignant tumors (TEC). Scale bar equal 100 <i>μ</i>m. (b) Expression of CTAs, Oct4, and Nanog in mouse ES, EG, and EC cells and EBs. (c) CTA expression profiles of germ line cells isolated from embryos of E 7.5, E 11.5 and E 14.5 stages.</table>

Stem Cells International

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Figure 5

Figure 5: Expression Patterns of Cancer-Testis Antigens in Human Embryonic Stem Cells and Their Cell Derivatives Indicate Lineage Tracks 