Small Molecules Greatly Improve Conversion of Human-Induced Pluripotent Stem Cells to the Neuronal Lineage
Figure 2
(a) Representative image of the quality of iPSC colonies used to produce EBs: distinct border with little to no differentiation. The recommended size for EB formation should be double the size as the depicted colony, approximately 2 mm in diameter. Scale bar 100 μm (b) In-control and PD-specific cell lines (Control and PD), EBs were lacking that compact structure and round borders when cultured without Dor/SB; EBs were found to be round, uniform in the presence of Dor/SB.
