Tissue Engineering for Rotator Cuff Repair: An Evidence-Based Systematic Review

Table 3

Clinical outcomes.

Study	Outcome measures	Pre-op.	3 days	1 month	3 months	6 months	12 months	16 months	24 months
Castricini et al., 2011 [17]	Constant score									𝑃 value
	Control group	42.9 (22–55)						88.4 (54–100)		<0.001
	PRP group	42 (30–53)						88.4 (72–99)		<0.001
	𝑃 value							0.44
Randelli et al., 2011 [30]	Constant score
	Control group	42.2±15.2			57.8±11	72.3±12.6	75.7±9.5		78.7±10
	PRP group	44±16.5			65±9	73.1±8.7	78.3±6.4		82.4±6.3
	𝑃 value	0.6			0.02	0.7	0.3		0.1
	UCLA
	Control group	14.5±5.6			24.2±4.9	29.2±4.9	31±4.1		31.3±4.1
	PRP group	15.3±5.9			26.9±3	30.6±4.1	31.2±5.2		33.3±2.2
	𝑃 value	0.6			0.03	0.3	0.7		0.06
	SER (Kg)
	Control group	2.3±2			2.1±1.3	3.3±1.3	3.7±1.5		4±1.9
	PRP group	1.9±1.7			3±1.6	3.9±2.1	4.2±2.8		4.3±2.3
	𝑃 value	0.4			0.04	0.2	0.5		0.5
	SST
	Control group	4.7±2.8			7.1±2.7	10.5±2.3	10.6±1.5		10.9±1.4
	PRP group	4.8±3.1			8.9±2.2	10.6±1.4	11.1±0.9		11.3±0.9
	𝑃 value	0.9			0.02	0.9	0.3		0.3
	VAS
	Control group	6.4±2	6.3±2.8	2.4±2.6
	PRP group	4.8±2	4±3.2	1.1±2.2
	𝑃 value	0.003	0.007	0.01
Jo et al., 2011 [29]	Constant Score
	Control group	50.78±16.04			46.10±17.75	64.56±15.98	81.36±11.97	82.00±13.02
	PRP group	46.47±16.50			33.47±14.39	63.36±11.73	77.65±13.02	79.12±13.42
	𝑃 value	0.397			0.036	0.910	0.493	0.476
	UCLA
	Control group	16.78±4.73			22.00±4.01	25.94±4.84	29.77±4.36	30.83±4.96
	PRP group	15.89±4.98			18.00±7.47	26.27±4.43	30.12±6.04	31.78±6.15
	𝑃 value	0.558			0.061	0.827	0.708	0.579
	ASES
	Control group	49.60±17.74			60.58±16.33	71.75±18.21	89.19±10.73	89.92±17.03
	PRP group	43.95±20.44			46.22±20.06	72.63±13.63	86.26±19.95	87.61±24.83
	𝑃 value	0.343			0.031	0.530	0.712	0.744
	DASH
	Control group	45.69±25.51			38.83±20.14	23.80±16.74	9.20±9.87	8.48±14.05
	PRP group	52.85±25.29			49.61±23.12	24.85±16.52	12.84±18.89	13.19±25.45
	𝑃 value	0.369			0.166	0.703	0.588	0.473
	SST
	Control group	5.17±2.99			5.40±3.57	9.06±5.45	10.64±1.71	10.57±1.73
	PRP group	4.63±3.29			4.40±2.50	8.36±2.25	9.59±2.85	9.83±3.31
	𝑃 value	0.579			0.369	0.982	0.206	0.355
	SPADI
	Control group	46.25±24.05			39.50±23.02	25.71±15.52	9.83±10.59	10.08±16.32
	PRP group	54.47±28.72			56.33±23.97	28.69±14.29	11.72±18.22	12.03±24.96
	𝑃 value	0.318			0.045	0.745	0.869	0.673