Review Article

Capability of Tissue Stem Cells to Organize into Salivary Rudiments

Figure 1

Brief overview of salivary gland development in mice. Schematic diagram of the 4 stages of salivary gland development: initial bud, pseudoglandular, canalicular, and terminal bud stage. Laminin-producing epithelia in end buds are indicated in light grey (pseudoglandular stage). Laminin-producing epithelia are only present in end buds but not in the stalk portion during BrM. A schematic diagram of the 3 steps in branching morphogenesis, stalk elongation, cleft formation, and dichotomization is also shown. Salivary mesenchyme is indicated in dark grey, and epithelia in white. See text for explanation. Abbreviations: mes: mesenchyme; e: epithelium; e.b: epithelial bud.
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