Stimulation of Cultured H9 Human Embryonic Stem Cells with Thyroid Stimulating Hormone Does Not Lead to Formation of Thyroid-Like Cells

Table 1

Markers and their description indicating pluripotency, three germ layers, and thyroid tissue.

Pluripotency	Ability to give rise to all tissues of the body	Oct3/4	POU class 5 homeobox 1
		Nanog	Nanog homeobox
Ectoderm	Nervous system, neural crest and its derivatives, epidermis, eye, salivary, and skin glands	PAX6	Paired box 6
		SOX1	SRY-box 1
Mesoendoderm	Gives rise to mesoderm and endoderm	T	T, brachyury homolog
Mesoderm	Connective tissue, muscles, reproductive system, spleen, peritoneum, urinary system, mesothelium, heart	TBX6	T-box 6
		KDR	kinase insert domain receptor
Definitive endoderm	Digestive and respiratory tracts, endocrine glands, and organs such as the liver and pancreas	SOX17	SRY-box 17
		FOXA2	Forkhead box A2
Thyroid tissue	Thyrocytes within thyroid gland derived from definitive endoderm	TSHR	Receptor to TSH
		TPO	Thyroperoxidase
		NIS	Sodium-iodine symporter