Development of a Functional Schwann Cell Phenotype from Autologous Porcine Bone Marrow Mononuclear Cells for Nerve Repair
Figure 6
Series of confocal photographs showing BM-MNCs cultured in Neurobasal media supplemented with NRG1-III increase the expression of myelin lipid. Using the myelin-lipid marker, FluoroMyelin, there was an increase in fluorescence staining (red) in the 10 nM NRG1-III 48-hr treated 6-day old cultures of BM-MNC-derived Schwann cells (b) compared to untreated cells (a). A human Schwann cell line was used as a positive control (c); nuclei (blue) are stained with DAPI.
