Clinical Study

Multipotent Mesenchymal Stromal Cells for the Prophylaxis of Acute Graft-versus-Host Disease—A Phase II Study

Table 1

Characteristics of the patients and treatments.

Group characteristicsFirst group (1)Second group (2)
Standard GVHD prophylaxisStandard GVHD prophylaxis + MMSCs

Sex of patient, male/female7/118/11

Median age, years (range)29 (19–60)34 (20–63)

Diagnosis, n
 AML/MDS1014
 ALL42
 CML33
 CLL1

Disease stage, n
 complete remission1519
 non-complete remission30

Conditioning regimen, n
 RIC46
 MAC1413

 Observation time, months3.5–30.52.5–32

AML: acute myeloid leukemia, MDS: myelodysplastic syndrome, ALL: acute lymphoid leukemia, CML: chronic myeloid leukemia, CLL: chronic lymphoid leukemia, RIC: reduced intensity conditioning, MAC: myeloablative conditioning.