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Stem Cells International
Volume 2012 (2012), Article ID 975871, 12 pages
Markers for Characterization of Bone Marrow Multipotential Stromal Cells
Academic Unit of the Musculoskeletal Diseases, St. James's University Hospital, Leeds Institute of Molecular Medicine, University of Leeds, Leeds LS9 7TF, UK
Received 26 January 2012; Accepted 29 February 2012
Academic Editor: Selim Kuçi
Copyright © 2012 Sally A. Boxall and Elena Jones. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [66 citations]
The following is the list of published articles that have cited the current article.
- Jiang Li, Mohamed B. Ezzelarab, and David K. C. Cooper, “Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantation,” Xenotransplantation, vol. 19, no. 5, pp. 273–285, 2012.
- P. Monica Tsimbouri, Rebecca J. McMurray, Karl V. Burgess, Enateri V. Alakpa, Paul M. Reynolds, Kate Murawski, Emmajayne Kingham, Richard O. C. Oreffo, Nikolaj Gadegaard, and Matthew J. Dalby, “Using Nanotopography and Metabolomics to Identify Biochemical Effectors of Multipotency,” Acs Nano, vol. 6, no. 11, pp. 10239–10249, 2012.
- Chiara Sassoli, Sandra Zecchi-Orlandini, and Lucia Formigli, “Trophic Actions of Bone Marrow-Derived Mesenchymal Stromal Cells for Muscle Repair/Regeneration,” Cells, vol. 1, no. 4, pp. 832–850, 2012.
- Yao-Chun Wang, Guang-Ying Dong, Li Li, Yang Xiao, Hua Han, Shu-Hong Wang, Ya-Ning Wei, De-Wei Du, Hao Xu, Chun-Chen Gao, Min-Hua Zheng, Juan Xie, and Jun-Chang Li, “Notch-RBP-J signaling is required by bone marrow stromal cells for the treatment of acute graft versus host disease,” Stem Cell Research, vol. 11, no. 2, pp. 721–735, 2013.
- K. Nakamura, A. Yoshimura, T. Kaneko, K. Sato, and Y. Hara, “ROCK inhibitor Y-27632 maintains the proliferation of confluent human mesenchymal stem cells,” Journal of Periodontal Research, vol. 49, no. 3, pp. 363–370, 2013.
- Yi-Zhou Huang, Jia-Qin Cai, Feng-Juan Lv, Hong-Lei Xie, Zhi-Ming Yang, Yong-Can Huang, and Li Deng, “Species variation in the spontaneous calcification of bone marrow-derived mesenchymal stem cells,” Cytotherapy, vol. 15, no. 3, pp. 323–329, 2013.
- Hal Sternberg, Jennifer Kidd, James T. Murai, Jianjie Jiang, Ariel Rinon, Isaac E. Erickson, Walter D. Funk, Qian Wang, Karen B. Chapman, C. Thomas Vangsness, and Michael D. West, “Seven diverse human embryonic stem cell-derived chondrogenic clonal embryonic progenitor cell lines display site-specific cell fates,” Regenerative Medicine, vol. 8, no. 2, pp. 125–144, 2013.
- Julia A. Paxson, Alisha M. Gruntman, Airiel M. Davis, Christopher M. Parkin, Edward P. Ingenito, and Andrew M. Hoffman, “Age Dependence of Lung Mesenchymal Stromal Cell Dynamics Following Pneumonectomy,” Stem Cells and Development, vol. 22, no. 24, pp. 3214–3225, 2013.
- Per Anderson, Ana Belen Carrillo-Galvez, Angelica Garcia-Perez, Marien Cobo, and Francisco Martin, “CD105 (Endoglin)-Negative Murine Mesenchymal Stromal Cells Define a New Multipotent Subpopulation with Distinct Differentiation and Immunomodulatory Capacities,” Plos One, vol. 8, no. 10, 2013.
- Andrew Aldridge, Dimitrios Kouroupis, Sarah Churchman, Anne English, Eileen Ingham, and Elena Jones, “Assay validation for the assessment of adipogenesis of multipotential stromal cells-a direct comparison of four different methods,” Cytotherapy, vol. 15, no. 1, pp. 89–101, 2013.
- J. P. J. Rocke, and A. J. Roelofs, “Cell-based approaches to joint surface repair: a research perspective,” Osteoarthritis And Cartilage, vol. 21, no. 7, pp. 892–900, 2013.
- Yajuan Jiang, Sean R. R. Hall, Elizabeth Leary, Greg Yavanian, Sarah Eminli, David W. O'Neill, and Wayne A. Marasco, “Identification and Isolation of Small CD44-Negative Mesenchymal Stem/Progenitor Cells From Human Bone Marrow Using Elutriation and Polychromatic Flow Cytometry,” Stem Cells Translational Medicine, vol. 2, no. 8, pp. 567–578, 2013.
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- Karim M Fawzy El-Sayed, Sebastian Paris, Christian Graetz, Neemat Kassem, Mohamed Mekhemar, Hendrick Ungefroren, Fred Fändrich, and Christof Dörfer, “Isolation and characterisation of human gingival margin-derived STRO-1/MACS+ and MACS− cell populations,” International Journal of Oral Science, 2014.
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- Rafael Kramann, and Benjamin D. Humphreys, “Kidney Pericytes: Roles in Regeneration and Fibrosis,” Seminars in Nephrology, vol. 34, no. 4, pp. 374–383, 2014.
- O. G. Davies, P. R. Cooper, R. M. Shelton, A. J. Smith, and B. A. Scheven, “A comparison of the in vitro mineralisation and dentinogenic potential of mesenchymal stem cells derived from adipose tissue, bone marrow and dental pulp,” Journal of Bone and Mineral Metabolism, 2014.
- Elena Jones, and Aileen Crawford, “High chondrogenic potential of synovial fluid–derived mesenchymal stromal cells,” Cytotherapy, 2014.
- Riccardo Schweizer, Pranitha Kamat, Dennis Schweizer, Cyrill Dennler, Shengye Zhang, Jonas T. Schnider, Souzan Salemi, Pietro Giovanoli, Daniel Eberli, Volker Enzmann, Dominique Erni, and Jan A. Plock, “Bone marrow-derived mesenchymal stromal cells improve vascular regeneration and reduce leukocyte-endothelium activation in critical ischemic murine skin in a dose-dependent manner,” Cytotherapy, 2014.
- Sebastian Raeth, Benedetto Sacchetti, Georg Siegel, Ulrike A. Mau-Holzmann, Jan Hansmann, Gabriele Vacun, Thomas G. Hauk, Klaus Pfizenmaier, and Angelika Hausser, “A Mouse Bone Marrow Stromal Cell Line with Skeletal Stem Cell Characteristics to Study Osteogenesis In Vitro and In Vivo,” Stem Cells and Development, vol. 23, no. 10, pp. 1097–1108, 2014.
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- C E Weber, A N Kothari, P Y Wai, N Y Li, J Driver, M A C Zapf, C A Franzen, G N Gupta, C Osipo, A Zlobin, W K Syn, J Zhang, P C Kuo, and Z Mi, “Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer,” Oncogene, 2014.
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- H Kasashima, M Yashiro, H Nakamae, G Masuda, H Kinoshita, T Morisaki, T Fukuoka, T Hasegawa, K Sakurai, T Toyokawa, N Kubo, H Tanaka, K Muguruma, M Ohira, T Nakane, M Hino, and K Hirakawa, “Bone marrow-derived stromal cells are associated with gastric cancer progression,” British Journal of Cancer, 2015.
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- M. T. Ortega, B. Jeffery, J. E. Riviere, and N. A. Monteiro-Riviere, “Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells,” Journal of Applied Toxicology, 2015.
- Richard J. Cuthbert, Peter V. Giannoudis, Xiao N. Wang, Lindsay Nicholson, David Pawson, Anatole Lubenko, Hiang B. Tan, Anne Dickinson, Dennis McGonagle, and Elena Jones, “Examining the Feasibility of Clinical Grade CD271(+) Enrichment of Mesenchymal Stromal Cells for Bone Regeneration,” Plos One, vol. 10, no. 3, 2015.
- Francesca Bortolotti, Laura Ukovich, Vahid Razban, Valentina Martinelli, Giulia Ruozi, Barbara Pelos, Franca Dore, Mauro Giacca, and Serena Zacchigna, “In Vivo Therapeutic Potential of Mesenchymal Stromal Cells Depends on the Source and the Isolation Procedure,” Stem Cell Reports, 2015.
- Ana R. Remacha, Rosa Bolea, Natalia Fernández-Borges, Juan J. Badiola, Diego R. Mediano, Belén Marín, Inmaculada Martín-Burriel, Joaquín Castilla, Óscar López-Pérez, Clementina Rodellar, Francisco J. Vázquez, David Sanz-Rubio, and Pilar Zaragoza, “Characterization of mesenchymal stem cells in sheep naturally infected with scrapie,” Journal of General Virology, vol. 96, no. 12, pp. 3715–3726, 2015.
- Hemanth Akkiraju, and Anja Nohe, “Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration,” Journal of Developmental Biology, vol. 3, no. 4, pp. 177–192, 2015.
- Doreen Reichert, Jens Friedrichs, Steffi Ritter, Theresa Käubler, Carsten Werner, Martin Bornhäuser, and Denis Corbeil, “Phenotypic, Morphological and Adhesive Differences of Human Hematopoietic Progenitor Cells Cultured on Murine versus Human Mesenchymal Stromal Cells,” Scientific Reports, vol. 5, pp. 15680, 2015.
- Zhiyong Poon, Wong Cheng Lee, Guofeng Guan, Lin Myint Nyan, Chwee Teck Lim, Jongyoon Han, and Krystyn J. Van Vliet, “Bone Marrow Regeneration Promoted by Biophysically Sorted Osteoprogenitors From Mesenchymal Stromal Cells,” Stem Cells Translational Medicine, vol. 4, no. 1, pp. 56–65, 2015.
- Peng Deng, Xiaoping Xu, and Qianming Chen, “Stem Cells Contributing to Postnatal Skeletogenesis in the Mouse Bone Marrow,” Current Stem Cell Research & Therapy, vol. 10, no. 5, pp. 450–456, 2015.
- Liang Xie, Xin Zeng, Jing Hu, and Qianming Chen, “Characterization of Nestin, a Selective Marker for Bone Marrow Derived Mesenchymal Stem Cells,” Stem Cells International, vol. 2015, pp. 1–9, 2015.
- Russell Emmons, Grace M. Niemiro, Olatomide Owolabi, and Michael De Lisio, “Acute exercise mobilizes hematopoietic stem and progenitor cells and alters the mesenchymal stromal cell secretome,” Journal Of Applied Physiology, vol. 120, no. 6, pp. 624–632, 2016.
- Nan Wang, Zubin Zhou, Tianyi Wu, Wei Liu, Peipei Yin, Chenhao Pan, and Xiaowei Yu, “TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin,” Open Biology, vol. 6, no. 3, pp. 150258, 2016.
- Juliane Brun, Tanja Abruzzese, Bernd Rolauffs, Wilhelm K. Aicher, and Melanie L. Hart, “Choice of xenogenic-free expansion media significantly influences the myogenic differentiation potential of human bone marrow–derived mesenchymal stromal cells,” Cytotherapy, vol. 18, no. 3, pp. 344–359, 2016.
- Buddhadev Layek, Tanmoy Sadhukha, and Swayam Prabha, “Glycoengineered Mesenchymal Stem Cells as an Enabling Platform for Two-Step Targeting of Solid Tumors,” Biomaterials, 2016.
- Q Chen, P Shou, C Zheng, M Jiang, G Cao, Q Yang, J Cao, N Xie, T Velletri, X Zhang, C Xu, L Zhang, H Yang, J Hou, Y Wang, and Y Shi, “Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?,” Cell Death and Differentiation, 2016.
- Yang Zhou, Li Fang, Yanting Yu, Jing Niu, Lei Jiang, Hongdi Cao, Qi Sun, Ke Zen, Chunsun Dai, and Junwei Yang, “Erythropoietin protects the tubular basement membrane by promoting the bone marrow to release extracellular vesicles containing tPA-targeting miR-144,” American Journal Of Physiology-Renal Physiology, vol. 310, no. 1, pp. F27–F40, 2016.
- Qin Shen, Yong Yin, Qing-Jie Xia, Na Lin, You-Cui Wang, Jia Liu, Hang-Ping Wang, Apiradee Lim, and Ting-Hua Wang, “Bone Marrow Stromal Cells Promote Neuronal Restoration in Rats with Traumatic Brain Injury: Involvement of GDNF Regulating BAD and BAX Signaling,” Cellular Physiology And Biochemistry, vol. 38, no. 2, pp. 748–762, 2016.
- Wanqiu Chen, David J. Baylink, K. -H. William Lau, and Xiao-Bing Zhang, “Generation of Mesenchymal Stem Cells by Blood Cell Reprogramming,” Current Stem Cell Research & Therapy, vol. 11, no. 2, pp. 114–121, 2016.