New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatric Orthopaedics

<table>Multipotent differentiation of BM hMSCs. The commitment and differentiation of hMSCs towards osteogenic, chondrogenic, adipogenic, or myogenic lineage are regulated by specific transcription factors (indicated in blue). ALP, alkaline phosphatase; Col-I, type I collagen; OPN, osteopontin; BMP, bone matrix protein; OC, osteocalcin; Col-II, type II collagen; Col-X, type X collagen; MMP-3, matrix metalloproteinase-3.</table>

Stem Cells International

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Figure 1: New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatric Orthopaedics 

Figure 1 | New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatric Orthopaedics 