Review Article
Emerging Therapeutic Strategies for Targeting Chronic Myeloid Leukemia Stem Cells
Table 1
Summary of the tyrosine kinase inhibitors and their effects on T315I.
| TKI | Originally termed | TKI generation | Acts on T315I |
| Imatinib | STI571 | First | No | Dasatinib | BMS-354825 | Second | No | Nilotinib | AMN107 | Second | No | Bosutinib | SKI-606 | Second | No | Ponatinib | AP24534 | Third | Yes |
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