MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation

Figure 2

Antibody- and peptide-based cell painting. Therapeutic cells are harvested and “painted” either by a two-step process where the cells are first coated with lipidated protein A (or G) and then incubated with targeting antibody, or a one-step process where the cells are coated with a peptide-targeting molecule that contains a lipid moiety. The coated cells are then reintroduced into the patient where the cells are directed towards specific tissues or organs.