Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome Model
Figure 5
Transmission electron microscopy findings of cellular injury observed in PBS-treated rats. Apoptotic cell (arrows) observed in PBS-treated rat cornea (a). Swelling of cells and lytic focuses in cell cytoplasms (thick arrow) were observed. Condensation of mitochondrial matrix, dilatation of smooth endoplasmic reticulum, and decreased secretory granules (thin arrow) were observed in cells (b). Peripheral migration, condensation of chromatins, and irregular expansion of perinuclear cisternas (thick arrow) were observed in nucleus of cells although there were intact desmosomes (thin arrow) between cells (c) (Joel JEM-1400 model, magnification (a), (b): ×5000 and (c): ×12000).
