Bone Marrow-Derived Multipotent Stromal Cells Attenuate Inflammation in Obliterative Airway Disease in Mouse Tracheal Allografts
Figure 6
Immunomodulation by MSCs does not require epithelial engraftment. Immunohistochemical staining was performed to determine epithelial engraftment of GFP-MSCs in transplanted trachea. (a) shows positive GFP-staining of tracheal epithelium (brown color indicated by a solid arrow) and parenchymal cells of a trachea section from GFP-mouse. (b) shows negative GFP-staining of tracheal epithelium (indicated by an empty arrow) from IV + T control group. (c) shows absence of GFP-MSCs on tracheal epithelium (indicated by an empty arrow) from IV + T MSC-treated group.
