The Role of MicroRNAs in Cardiac Stem Cells

Figure 2

Summary diagram illustrating the cellular interactions of various miR subtypes and clusters with regard to their role of regulating the differentiation and proliferation potentials of cardiac stem cells (CSCs) and progenitor cells (CPCs). These miRs target specific transcription factors and cardiac genes (yellow circles) and inhibit their protein expression, causing a downstream effect on stem cell differentiation and proliferation (inhibition is indicated by the red arrows and activation is indicated by blue arrows).