A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence

<div>Differentially expressed genes show regional specific expression in the chorion of E7.5 embryos.<i> In situ</i> hybridisation analysis on sagittal sections of E7.5 mouse embryos reveals specific expression of<i> Eomes</i> as positive control and novel TSC marker genes<i> Bok/Mtd</i>,<i> Cldn26</i>,<i> Cyp26a1, Duox2</i>,<i> Duoxa2</i>,<i> Nr0b1</i>, and<i> Sox21</i>, in the entire chorion, or limited expression in the chorionic hinge (indicated by arrowheads). AlB, allantoic bud; Ch, chorion; PS, primitive streak; VE, visceral endoderm. Scale bar: 200 <i>μ</i>M.</div>

Stem Cells International

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Figure 6

Figure 6: A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence 