Review Article
Applications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative Diseases
Table 2
Associated genes in patients with neurodegenerative diseases.
| Disease types | Genes | References |
| Alzheimer’s disease | APP, PS1, PS2, APOE | [40–42] |
| Parkinson’s disease | GBA, LRRK2, PARK2, PARK7, PINK1, SNCA, UCHL1, MAPT | [43–45] |
| Amyotrophic lateral sclerosis | SOD1, FUS, TDP-43, C9ORF72 | [46–48] |
| Spinal muscular atrophy | SMN1, SMN2 | [49, 50] |
| Down syndrome | Trisomy 21 | [50, 51] |
| Huntington disease | HTT (CAG-type repetitive DNA sequences) | [52, 53] |
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