WNT/β-Catenin Signaling Is Required for Integration of CD₂₄₊ Renal Progenitor Cells into Glycerol-Damaged Adult Renal Tubules

Figure 2

Endogenous coexpression of CD24 and β-catenin/TCF reporter transgene following glycerol-induced renal injury in adult mice. (a–d) Kidney sections showing endogenous tubular cells of glycerol-treated mice: (a) immunostaining for reporter β-galactosidase (green); (b) immunostaining for CD24 (red); (c) nuclear staining with DAPI; (d) merged images showing coexpression of β-galactosidase and CD24 in tubular cells (white arrows). (e–h) Kidney sections showing endogenous tubular cells in control (PBS injected) mice: (e) β-galactosidase reporter (green); (f) CD24 (red); (g) DAPI; (h) merge. Scale bars: 50 μm.

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