WNT/β-Catenin Signaling Is Required for Integration of CD₂₄₊ Renal Progenitor Cells into Glycerol-Damaged Adult Renal Tubules

Figure 3

CD24 expression in embryonic mouse kidney. (a) PE-red-tagged CD₂₄₊ cells are seen predominantly in the nephrogenic zone of E15 mouse kidney. (b-c) In E18 kidney from Hoxb7-GFP transgenic mice, CD₂₄₊ cells (red) are seen in the cap mesenchyme associated with ureteric bud branch tips (green). (d-e) At high power, CD₂₄₊ cells (red) are seen within comma-shaped (C) and S-shaped (S) bodies of emerging nephrons. (f) Occasional CD₂₄₊ cells (red) are seen within the ureteric bud trunk (green) of E18 Hoxb7-GFP mice. Scale bar: 50 μm.

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