Review Article

Making Blood: The Haematopoietic Niche throughout Ontogeny

Figure 3

Cellular interactions within the adult bone marrow niche. The bone marrow niche is home to a variety of cell types that promote or inhibit the maintenance of HSCs and haematopoietic progenitors. The endosteal niche and perivascular niche can be clearly discerned. Adipocytes fill the marrow with age, inhibiting blood cell production.