Research Article

CXCL13 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Inhibiting miR-23a Expression

Figure 1

Stimulation of osteogenic differentiation of mesenchymal stem cells by CXCL13. Mouse bone marrow mesenchymal stem cells (BMSCs) were incubated in differentiation media with or without recombinant CXCL13 protein (20 ng/mL) and on day 17, the analysis of osteogenesis and protein expression analysis was performed. (a) Representation of calcium nodes by alizarin red staining. (b) ALP activity. (c) Expression of Runx2 using western blot assays. All values represent means ± SD (). compared with control groups treated without CXCL13 recombinant protein.
(a)
(b)
(c)