Research Article

Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction

Figure 1

Generation and characterization iPS cells from human fetal liver fibroblasts (FLF) with Oct4, Sox2, Klf4, and c-Myc (OSKM) and Oct4, Sox2, Nanog, and Lin-28 (OSNL) and also from human bone marrow MSCs with OSKM using lentiviral vectors. iPSCs stained positive for human OCT4 and SOX2. DAPI was used to stain the nuclei and merged with phase-contrast. Expression of SSEA-4 is shown in histograms.