Research Article

Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction

Figure 3

Antigen phenotype, proliferation rate, and functional characterization of hiPSC-MSCs. (a) Immunophenotype of the three hiPS-MSCs lines generated. Representative flow cytometry analysis of hBM-MSCs, FLF-iPSC-MSCs (OSKM), FLF-iPSC-MSCs (OSNL), MSC-iPSC-MSCs (OSKM), and MSC-derived iPSC line MSC-related markers CD73, CD90, and CD105 and hematopoietic CD45, CD34, and CD19 were assessed (solid histogram). (b) In vitro cell growth, measured as cumulative population of hiPSC-MSCs and BM-MSCs derived from 3 different donors (LM02, LM05, and LM06).
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