Review Article

Bottlenecks in the Efficient Use of Advanced Therapy Medicinal Products Based on Mesenchymal Stromal Cells

Table 1

Summary of mesenchymal stroma cell nomenclature.

Nomenclature Year Authors’ references

CFU-F and osteogenic stem cells 1974 Friedenstein et al. [10]
Stromal stem cells 1988 Owen and Friedenstein [16]
Mesenchymal stem cells 1991 Caplan [17]
Mesenchymal progenitor cells 1999 Dennis et al. [18]
Skeletal stem cells 2000 Bianco and Robey [19]
MAPCs and mesodermal progenitor cells 2002 Jiang et al. [20]
Multipotent mesenchymal stromal cells 2006 Dominici et al. (ISCT) [21]
Medicinal signalling cells 2010 Caplan [22]

CFU-F: colony-forming unit fibroblasts; MAPCs: multipotent adult progenitor cells; ISCT: International Society for Cell Therapy.