Proangiogenic Features of Mesenchymal Stem Cells and Their Therapeutic Applications

Figure 3

Angiogenic potency of MSCs. MSCs could promote angiogenesis either by paracrine effects or by transdifferentiation. The secretion of cytokines could enhance the proliferation and migration of endogenous endothelial cells. Moreover, MSCs may transdifferentiate into lineage with functional and phenotypic features of ECs and participate in angiogenesis directly.