Review Article

Nanoparticles-Assisted Stem Cell Therapy for Ischemic Heart Disease

Table 2

Evaluation of NPs labeling agents for stem cells.

NPs labeling modalityAdvantagesDisadvantages

MRI modalityHigh spatial resolution (25–100 μm) [57, 58]
Excellent tissue penetration depth (no limit) [58]
Allowing quantitative measurements
Low sensitivity (mM to μM) [57, 58]
Long scan time (minutes to hours) [59]
High cost

Optical modalityHigh sensitivity (nM to pM) [58]High scattering
High absorption in tissue
Short penetration depth (<4 cm from skin surface) [60]