Lovastatin Decreases the Expression of CD133 and Influences the Differentiation Potential of Human Embryonic Stem Cells

Figure 7

CD133 expression was crucial for proper differentiation into embryoid bodies. CD133+ and CD133− cell subpopulations were enriched using the magnetic beads separation method from untreated hES cells and the formation of EB was initiated. (a) Morphology of the formed structures on day five. (b) Formed EB and cell structures were analysed for the expression of CD184, nestin, and SOX2.

(a)

(b)