Primordial Germ Cells: Current Knowledge and Perspectives

Table 1

Summarized genes that participate into PGC development.

Full name	Alternate names	Time of expression	Location of coded protein	References
Tissue nonspecific AP (Tnap)		E7.25-14	At the cell surface, linked to the cell membrane via a phosphatidylinositol glycan linkage	[22]
Stella	Developmental pluripotency-associated 3 or Dppa3 or Pgc7	E7.5	Protein that may shuttle between the nucleus and cytoplasm	[8, 21]
Fragilis		E7.5	Transmembrane protein	[8, 21]
B-lymphocyte-induced maturation protein 1 (Blimp1)	Pr domain containing protein 1 (Prdm1)	E6.25	Cytoplasmic transcriptional repressor	[24]
Prdm14	Pr domain containing protein 14	E6.25	Transcriptional regulator	[25]
Mouse Vasa ortholog (Mvh)		E13.5(10.5) end of the migratory phase of PGC development	Cytoplasm	[9]
Deleted in azoospermia-like (DAZL)		E12.5(11.5)	Cytoplasmic protein	[44–52]