The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells

Figure 5

CD163 acted upstream FGF-2 in BMSC differentiation into a vascular endothelial lineage. (a) Western blot analysis of the protein level of FGF-2 after overexpression of CD163. (b) Relative protein levels of FGF-2 were calculated based on densitometry analysis. Data are mean ± SEM. , versus control (Ctr), . (c) A conceptual schematic of CD163 involved in the differentiation of BMSCs into a vascular endothelial lineage. Hmbox1 increases the expression of CD163, which promotes BMSC differentiation into vascular endothelial-like cells by enhancing FGF-2.

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