Transcranial Direct Current Stimulation Modulates Neurogenesis and Microglia Activation in the Mouse Brain

Figure 3

Multisession anodal tDCS at low charge density downregulates the constitutive activation of microglia. (a) Multisession tDCS with 99 kC/m² did not cause focal cortical lesions (scale bar represents 1 mm). (b) Microglia expressing Iba1 displayed an amoeboid morphology irrespective of stimulation polarity (scale bar represents 20 µm). (c) The number of Iba-positive microglia in the cortex was significantly decreased following multisession anodal tDCS both ipsilateral and contralateral to stimulation ().

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