Theoretical and Practical Issues That Are Relevant When Scaling Up hMSC Microcarrier Production Processes

<div>Results from the proof-of-concept cultivation in a BIOSTAT CultiBag RM 2L. (a) Comparison of the expansion factors in the BIOSTAT CultiBag RM 2L and the control spinner flask. The error bars represent the standard deviation. (b) DAPI staining picture of an aggregate at the end of the cultivation in the BIOSTAT CultiBag RM 2L. White bare = 500 <i>μ</i>m.</div>

Stem Cells International

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Figure 8

Figure 8: Theoretical and Practical Issues That Are Relevant When Scaling Up hMSC Microcarrier Production Processes 