Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival

Figure 2

MSCs engineered to enhance migratory properties. Increased MSC migration could be accomplished by membrane-bound receptor engineering (i.e., CXCR1, CXCR4, and CXCR7), water channel receptors (Aqp1), or the upregulation of defined nuclear receptors (i.e., Nur77 and Nurr1).