Advances in the Treatment of Ischemic Diseases by Mesenchymal Stem Cells
Table 1
Summary of important factors and efficacy of MSCs therapeutics for ischemic cerebrovascular disease, ischemic cardiomyopathy ICM, and diabetic foot from recent publications.
Name of ischemic disease
MSC source
Transplantation route
Transplantation timing and dose
Major efficacy
Mechanisms
Ischemic cerebrovascular disease
Bone marrow MSCs [26, 29, 37, 42], adipose-derived MSCs [27, 31, 41], and umbilical cord MSCs [30]
Intracranial transplantation [28], intracerebral injection [26], and intracerebral injection [27]