Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34⁺ Cells

Figure 2

Bioinformatic analyses of miRNAs in MSC-MVs. (a) The overall expression level of miRNAs in MSC-MVs. (b) Gene Ontology enrichment analysis of the potential targets of expressed miRNAs in MSC-MVs. (c) A schematic illustration representing miRNAs and potential targets involved in regulation of the Wnt/β-catenin pathway. Blue rectangles: genes that are reported to inhibit the Wnt/β-catenin pathway and are expressed in CB-derived HSCs. Yellow triangles: relatively highly expressed miRNAs in MSC-MVs. Green ellipses: Wnt/β-catenin pathway. Black and gray lines indicate inhibitory effects.

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