Review Article

Three-Dimensional Bioprinting Nanotechnologies towards Clinical Application of Stem Cells and Their Secretome in Salivary Gland Regeneration

Table 1

List of secretome components (matrix peptides, cytokines, growth factors, and enzymes) from SG cell lines that can be potentially used in SG regeneration strategies. More details about each secretome component can be found in [18, 23]. ALDH3: aldehyde dehydrogenase 3; EDA: ectodysplasin A; EGF: epidermal growth factor; FGF: fibroblast growth factor; IGF: insulin growth factor; IL: interleukin; SHH: sonic hedgehog; SCF: stem cell factor.

Secretome componentsReferences

ALDH3 activator[24]
EDA[25]
EGF[26]
FGF2[27]
FGF7[28, 29]
FGF10[29ā€“31]
Heparan sulfate[31, 32]
IGF1[33]
IL-6[34]
SHH[35]
SCF[32]
Wnt[36ā€“38]